Lessons from London and Berlin: Designing A Scalable Gene Therapy Approach for HIV Cure
Peterson CW, Kiem HP. Cell stem cell. 2019;24(5):685-7. Epub 2019/05/06. doi: 10.1016/j.stem.2019.04.010. PubMed PMID: 31051132.
Recently in Nature, Gupta et al. (2019) reported that a second patient has achieved HIV-1 remission/functional cure after allogeneic hematopoietic stem cell transplantation from a donor carrying a mutation in the CCR5 coreceptor. We highlight both patients' treatments and summarize efforts to develop a broader, more patient-friendly approach.