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We are scientists, clinicians and community working together
to find a cure for HIV.

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defeatHIV is
Cell and Gene Therapy for HIV Cure

defeatHIV is a Collaboratory of leading scientists and clinicians in the fields of HIV, cell and gene therapies, pre-clinical models, and clinical research, partnered with a strong team of community advocates, united by a shared vision: finding a cure for HIV. Founded in 2011 and led by Drs. Keith Jerome and Hans-Peter Kiem at Fred Hutchinson Cancer Research Center in Seattle, WA, defeatHIV continues pushing HIV cure research and advocacy forward.

Fred Hutch is the birthplace of bone marrow transplantation and a pioneering hub of immunotherapy development.The late Dr. E. Donnall “Don” Thomas, a founding faculty member of Fred Hutch, received the 1990 Nobel Prize in physiology or medicine for establishing bone marrow and blood stem cell transplantation as a lifesaving treatment for leukemia and other blood diseases.

defeatHIV investigators are extending this legacy to HIV, trying to understand how bone marrow transplantation cured the HIV infection in Timothy Ray Brown. We are leveraging these insights to develop potent cell and gene therapies that aim to eliminate HIV from where it lies dormant in the body, and revolutionize the way HIV is treated.

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Those who are affected by research have a right to be involved in the research-making process

defeatHIV is achieving more with our community engagement initiatives than ever before. We work on many exciting projects to help improve the understanding of difficult science, and are very proud of the progress we continue to make. Learn more about what we do, who we help, and how we work every day to promote positive change.


One Step at a Time

Hugely popular last seven years, our educational events have drawn hundreds of people who want to interact more with the notable scientists and research participants dedicated to the same goal: curing HIV.


Helping Researchers, Helping Community

defeatHIV CAB’s mission is to assure stakeholder perspectives, especially those of people living with HIV (PWH), are incorporated into defeatHIV’s decisions and activities.


Reinforcing our Commitment

Using community-based participatory research (CBPR) methods, we seek to assess the acceptability of potential HIV cure research interventions, with a focus on cell and gene therapy.

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Upcoming Events

  • Pre CROI Community HIV Cure Research Workshop - Session 2
    Pre CROI Community HIV Cure Research Workshop - Session 2
    Fri, Mar 05
    Mar 05, 2021, 9:00 AM – 11:00 AM PST
    Mar 05, 2021, 9:00 AM – 11:00 AM PST
    Our second session is dedicated to cell and gene therapy approaches to curing HIV. We'll give you an overview of the entire field, and then focus on some of the cutting edge work that has brought us closer to eradicating HIV from the body.
  • Pre-CROI Community HIV Cure Research Workshop - Session1
    Pre-CROI Community HIV Cure Research Workshop - Session1
    Thu, Mar 04
    Mar 04, 2021, 9:00 AM – 11:00 AM PST
    Mar 04, 2021, 9:00 AM – 11:00 AM PST
    An introduction to HIV cure-related research and discussions of community perspectives about a cure.
    Tue, Mar 02
    Mar 02, 2021, 5:30 PM – 9:30 PM PST
    Mar 02, 2021, 5:30 PM – 9:30 PM PST
    Join us every first Tuesday of the month via Zoom. Send an email to for more details.
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Contact Us

Interested in joining our Community Advisory Board?
Want to join our mailing list to receive updates on defeatHIV research and events?
Use the contact form to connect with us.

1100 Fairview Ave N, E5-110, Seattle, WA 98109

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